Oxyma Pure

OxymaPure® used with DIC produces peptides with increased yield and decreased epimerization when used as an alternative to HOBt.1 This safe, non-explosive auxiliary nucleophile works with carbodiimide coupling strategies to provide the best results for a peptide synthesis. Additionally, the use of DIC/Oxyma avoids side reactions associated with high levels of base (≥ 1 equiv. DIEA) using onium salt methods such as HBTU/DIEA.

Standard Specifications
  • Extremely fast acylation rates
  • Non-explosive (compared to HOBt)
  • Low cost
  • Highly soluble in peptide synthesis solvents


  • #S001-D 1 kg
    #S001-C 100 g
1. R. Subirós-Funosas, et al. (2009) Chem. Eur. J., 15, 9394.